diff --git a/CMakeLists.txt b/CMakeLists.txt
index e7fa35b9ecc..3812c207b5b 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -235,6 +235,15 @@ include(ProcessConfigurations)
 include(TryAppendCXXFlags)
 include(TryAppendLinkerFlag)
 
+# Redefine/adjust per-configuration flags.
+target_compile_definitions(core_interface_debug INTERFACE
+  DEBUG
+  DEBUG_LOCKORDER
+  DEBUG_LOCKCONTENTION
+  RPC_DOC_CHECK
+  ABORT_ON_FAILED_ASSUME
+)
+
 if(WIN32)
   #[=[
   This build system supports two ways to build binaries for Windows.
diff --git a/cmake/module/ProcessConfigurations.cmake b/cmake/module/ProcessConfigurations.cmake
index 7e2fc0080e9..52fca3cd1f7 100644
--- a/cmake/module/ProcessConfigurations.cmake
+++ b/cmake/module/ProcessConfigurations.cmake
@@ -119,14 +119,6 @@ endfunction()
 
 set_default_config(RelWithDebInfo)
 
-# Redefine/adjust per-configuration flags.
-target_compile_definitions(core_interface_debug INTERFACE
-  DEBUG
-  DEBUG_LOCKORDER
-  DEBUG_LOCKCONTENTION
-  RPC_DOC_CHECK
-  ABORT_ON_FAILED_ASSUME
-)
 # We leave assertions on.
 if(MSVC)
   remove_cxx_flag_from_all_configs(/DNDEBUG)