diff --git a/CMakeLists.txt b/CMakeLists.txt
index 4b21646ca18..35a7525b512 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -534,6 +534,13 @@ if(WERROR)
   unset(werror_flag)
 endif()
 
+# Prefer Unix-style package components over frameworks on macOS.
+# This improves compatibility with Python version managers.
+set(Python3_FIND_FRAMEWORK LAST CACHE STRING "")
+# Search for generic names before more specialized ones. This
+# improves compatibility with Python version managers that use shims.
+set(Python3_FIND_UNVERSIONED_NAMES FIRST CACHE STRING "")
+mark_as_advanced(Python3_FIND_FRAMEWORK Python3_FIND_UNVERSIONED_NAMES)
 find_package(Python3 3.10 COMPONENTS Interpreter)
 if(Python3_EXECUTABLE)
   set(PYTHON_COMMAND ${Python3_EXECUTABLE})