diff --git a/configure.ac b/configure.ac
index f0ebc50623..fb154e0b43 100644
--- a/configure.ac
+++ b/configure.ac
@@ -725,6 +725,10 @@ case $host in
 
      dnl We require Windows 7 (NT 6.1) or later
      AX_CHECK_LINK_FLAG([-Wl,--major-subsystem-version -Wl,6 -Wl,--minor-subsystem-version -Wl,1], [CORE_LDFLAGS="$CORE_LDFLAGS -Wl,--major-subsystem-version -Wl,6 -Wl,--minor-subsystem-version -Wl,1"], [], [$LDFLAG_WERROR])
+
+     dnl Avoid the use of aligned vector instructions when building for Windows.
+     dnl See https://gcc.gnu.org/bugzilla/show_bug.cgi?id=54412.
+     AX_CHECK_COMPILE_FLAG([-Wa,-muse-unaligned-vector-move], [CORE_CXXFLAGS="$CORE_CXXFLAGS -Wa,-muse-unaligned-vector-move"], [], [$CXXFLAG_WERROR])
      ;;
   *darwin*)
      TARGET_OS=darwin